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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436e5263da5f630404bb03d6c016e0ee081b7f280781d04983726a4e94aec6cd' 
  AND token = 'YfI+bcX7hRW8/kJZzWC7FJhh540zHF0iHDQ/4Z+QmCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}