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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e43e41b78bf40ddde836620ce25e557c05684793da88722672c84d93e7f9566' 
  AND token = 'EKwtZodTN90bF5NMkdTNyrewuQzelsQ0Pb4C4YeeCH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}