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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25da9047e0359c89a5907a87c06b6a64cf69d31cc72d06614f73379b54502a9' 
  AND token = 'ybAZLDDnnFVzi5n4ToPg+4ytzrmD79ZCAZG4XjJN7IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}