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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6b41adc14e3ea8bb3259a9c864df788b13164b2e7440edc3b753da930b8539' 
  AND token = 'H+GLG0g98f1MJcQenDytEAA3NEQUVf2R8Zsmp29GpHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}