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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1bb70a568e32c9cae16c243a57973f6a763f27f1a100a609495bd693b0be8d' 
  AND token = 'Z/Auqkn0IeRYwaLO2SHVsUBnmwINwBiGGk8PFN8A7Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}