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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54165792eda73646ab777937a153c51a3bc2c052bf52d8f1be9070dda1863d9a' 
  AND token = 'c347D/s504wXOgfIlG7HtNqwzGMqoG3u9cKhyaXyibo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}