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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24388638391f73b753bb44e2f1e4c38a782d23a5021b648b539815b24f65a0c2' 
  AND token = 'S9tctc2NR3ZLrNwOv+DrDz2htB1ytBMTcP+I8R7ON2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}