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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f068c270109ae3c25e48691cd68f05d6761ff160ba63b689f4a1c835f49e556' 
  AND token = 'RNCovwK1+xiZ1a26tz1AaAl4kuN0wYgS+dVaZr1qFuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}