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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88c89312b2170f3acc807e3f8ad5437ff1c94a0a7a1d778c54a6833c7c4002d' 
  AND token = '7+krbbX0Z9aKD3/QfQ1TpjTxg5OR+PWAwF9BjnT+8W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}