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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9370972d516fa663592dd39e340ec0e2e3e096fa73eb515e074e1ef132021a31' 
  AND token = 'Q+4b3J4JEDBV5KG1HyBgawfJsiwbXTbQ385D2mX05Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}