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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f8204c8834ba9cd80f0e4c4af53d75531ce4d2ffddbd4ab61f0d8bacdd21356' 
  AND token = 'ZOAO/h9vDY+csG6DcVf3AbC8haxdfJeESU1FVJDyF0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}