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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd003e70a0e30bd918627936e2f283a170a1f43c0b79d99ba73d72a2e179ea8ac' 
  AND token = 'kZqUO/sHkn5JQw2PI3PcPme6LEhCcL4r6DmKfqztLiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}