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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a246f00545639c9e2985b81864559dec6f6f4f7db6e8bebad7b702c4b66aeaf' 
  AND token = 'e25JJnDMPI8durx5aTsNU3D3hvyVKFylcDj7apuVVpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}