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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25edeb208eb5785082b45846d35aaf565219b0b57b69e36fab21814ff85c0f3' 
  AND token = 'rwaTgNQIVY41oFPIoLFUYm7G+b+1L0ru+qX8Hc6P0GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}