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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f183ff23b78d2105370ddfddbf263f7c2583af7513f618295c3618ebca7876' 
  AND token = 'ibIdrInqRKZ//vyEj/0MYuQNqi6p+70FANSfxU7a5Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}