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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463ed1236637a2ed9b6e30316443e72bf5d37019f7e53d41413e10a6a58960b9' 
  AND token = 'UGPi1/zzA+VNOi8aKXQ8ghyz/zreyX0Lmrpi46WImPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}