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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1703ee27cd21a9547cce6e726b03fa868d280e61871f39e5bbe54725ec9cae5' 
  AND token = '5qRWR6/IVH0tf9veAv8UZKS7gV9p11pUulcbR9+WKPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}