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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee52f37c9fc78466425c1521fb7cc7b49a87905b8ea17a196bd44ad24facc3d' 
  AND token = '5wZsObcrk5VxV1pPXvIkHX5SjtinjmTE3v0cvKUXyd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}