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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce723aa2f03417a8df6ee11c15ae2246a739cfd413c237ccd878c77a4674166' 
  AND token = '1dq5txUIMrP6a+XvsUcdvORASx5P1787nVxJ1ZjLXHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}