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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f7f4009d5a14e19a20075a0719da43f5b71d49535f1792a4fcd31d80968d19' 
  AND token = 'VsyMkHg2DaXrJjL1YVnJ4ntCZFZIUNWW4Ry1YKnfV2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}