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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c65cce083bb4403bebff8b0c56dc53c4d4f41610454ca48d646c96a52177dc5' 
  AND token = 'bis39K7xV6t+kM8Yk/6ef+gTHcHavgBO+aISIw0pQjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}