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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9632191c9988b8485d1505ab0578af71d9fe0b69a4b9028eb0a6c180a8b44d' 
  AND token = 'NvtR2FHt4ytV4yL/dsiYquCw041BWuPbJkfWeg+BJQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}