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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd73188e772ceb90fe6b625c7dc7e77c7f7c08fb53cefde3486232b1561fe88' 
  AND token = 'iJEPcpxwj4YTVulwDRKVstxzHeor3STz2RC88vG9MYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}