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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a63b8ee41f73534ed3555b6e95c98868edc90d79edccc53b37ad960beb4a8c9b' 
  AND token = 'oXS8xVJ+BDLXImsofIdTwalwnHnqCrQC/wRzxHsb7m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}