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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53a4f40bcae95a59042445ebd54b8ee058a7ae8fa1df799bdeb786343de1d29' 
  AND token = 'PmbNGVfJbRIIqvOKG43ToTMQzQ7l/NGA2j57IP0YFdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}