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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728576f424c279c5bd32b9578a60e10e3fd5a9e76a6684ab7a6d929bb36d8134' 
  AND token = 'ElM9ps7qXv3ZI5xKKZ46MQTweI0SBfMbrikuEagFhqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}