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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff212a2644b677080ed829424ce4e0b41a9645786c110bbbcadac8877312da3' 
  AND token = 'y3+nYfDzzBq6kmRx8jbbVqVrxm+XuPdbeRRbu6sKB6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}