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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb94abe7fd7cc903c8a1bca6e7380f5536e2da1882a3ad9c857ffda20b91c2b' 
  AND token = 'WItLjldz7YQxLRO7UCZUWRgP8Rmid0jwaUneZRfYAkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}