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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3857c513b5936997293bb303a3e03c8735259f05356ffd5c20b3e3e57fd1529' 
  AND token = '4fzYSPLB4bWOJI5jA9GeMQstZ7o9MKt+fDB9QQhLYIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}