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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c6fc3009e6ada6b71acbc00720bd2ec39fa4c0173af66add93662739e5eae7' 
  AND token = 'IVpI5zTLZCc7dVHd1l9QBRp5V9jNvlqE3SSUh+cdhoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}