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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e03eb8fc975fe4ec61b2b5de53a811fd222717fde24e614bcbcd2527efc089' 
  AND token = 'AHH1cmoViC1ukKNbY+AusRuf7yVfFJ7bcWI24KJP7Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}