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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cb2bc886b761a0de8f6ce61470b07a7dad247e55f25061fa1fe2c314467329a' 
  AND token = 'm7geZmSzbSFLuZTIxt7XGBK6hmZi5KJUrAfXyfPeaq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}