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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb41a5e6910576d82938df3c928d8cfbdd35a100622792dba640dbf2b0b5420' 
  AND token = 'HCSi83U2SXgQcTdnL/7Gh7bnYh6EI1lmm4iSbN3L2/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}