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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc74b5a2e87392f5e6ca0f08eac994a87135ff0c820b10a93d481fda5a0f6b1' 
  AND token = 'KAM8VT/0pp8+DWdFarscQy4tPYnxuXCoXsCJs6EbfDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}