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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a93f2f3caa6ca58808e5a14ad3e85399a521e94e7242c8b530a26a318ac5ec' 
  AND token = 'e2uCAbm0XMhvOADUKBFre4Ufp5ClI6L+h17Kb1NQf9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}