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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8709dde847ed308106238e7f8e54aea07f1b974347641777e19b115467c8f44' 
  AND token = 'CtJ3Ny5AgDhNFB9k7/Uf3u87cr1xjDTS+BSG7D2AB6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}