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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a1d4f62cddb05a61b17936b108f2a7dc96832c27d7da34009811a9eeb3be59' 
  AND token = 'dJyypeesu+ROB+9snm22PfiX4d6IC6lOS4CXLmDYU4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}