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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c90746024ed1cd0796322b0795fbc688c7f4df99695bf69413a266e91094f3' 
  AND token = 'RZZEbAGA6H6ST5akJcIibTTY6uoM0eURKMgJe/bvvAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}