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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6daa8ba2310639a511bbad58b54a8224375d8d36e16279fe08c2d2c88f8acf94' 
  AND token = 'I7I6mOYLRy0Aeb+IkQxgx0Ax+N2W6AOVN88EsDYQc2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}