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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65a0a17209b0ee14d3917dd04df9230186b57d76d67be58de6c56a2f1af2d68' 
  AND token = 'zXqLqkZmVJg4Dd6AXs5vPb9ySAQbI4U1dq5AcDxYmyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}