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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0017764ffbc09090ad145b83e010d45da11b05dc15373f5cf1b389054a4f76' 
  AND token = 'hq/KE6cERsDMIhG7Abbqm+8PfOCdzGD43dHV0JVISFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}