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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebeb7c97e6ffdbfa7ff322851709d25c89e94b306fc9d1617fe45ca161a09571' 
  AND token = 'KofY8gKSpmO6PnhSVJd6VZJaTwAs0M5uxCAaOwsSFfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}