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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2296a0d43999542f4adf8641c8e6b0ac7f09fc333c3b3d7b9b9bcdcf47308a' 
  AND token = 'oaOjrNNBS5T5vB4TwaOIDZWYwAc0aYjH7DHKh1qGCbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}