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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2a2e9e6257b9f8aaeaac44191df63b7d292a21c5e1c15c79329f76f5d25aae' 
  AND token = '1YTERxDz/TvAoY7wpyZTAphpZxvRrEYRjA9UPfqmK6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}