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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59002a9d45aa3295fca08c7170382eeace440eece2408833a553b49abb7edb28' 
  AND token = 'YZdAN+NPb2RYmAGMU8If6L9EvkuIJMs4aowUbYuuc2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}