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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a209b9b363beffc70412523665abcf5fc9edb1df53834d59a0c48d2b7039a03' 
  AND token = 'kaA/VfBoEEqI59RzirfPlmU5SqpO2gh9ox83ztoadjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}