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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef868f8657759aaa340e302c2d7af49315abd27ee1ff5b0270911e5e42f9461a' 
  AND token = '5ZTidfz/v5FA+kN8dv3s704iv4kj28qJ0RHArOByCQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}