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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2efa9cb9091c2162e931b596d7b3cb1552778f8262687dd65a5c3cfd6d3f3139' 
  AND token = 'xPyRgpMK5caM6DpIAROFfDim1hLH9E4uP514e12ymJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}