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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b7fc053d76aa20ddb56e504b7ee80e65c7f63ae85d3e2fb93e682a4390027c' 
  AND token = '+d9MLmGoP01AaNhNHspmSynxjLLV4Eh492ZfCtsmfxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}