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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0585333f107b99e8b7383ed1858c3529f8d4c729298d1a104f307ce031cf2620' 
  AND token = '4+Nrf2b54IwMvbX84tt+T1GigVXhgeOel0HZ75gLQrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}